Historique
Périodique
Recreational drug use and the risk of primary infertility
(Usage récréatif de drogue et risque d'infertilité.)
Auteur(s) :
MUELLER, B. A. ;
DALING J. R. ;
WEISS, N. S. ;
MOORE, D. E.
Année
1990
Page(s) :
195-200
Langue(s) :
Anglais
Refs biblio. :
12
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
CANNABIS
;
USAGE RECREATIF
;
SEXE FEMININ
;
STERILITE
;
REPRODUCTION
;
FACTEUR DE RISQUE
;
LSD
;
COCAINE
;
AMPHETAMINE
Thésaurus géographique
ETATS-UNIS
Note générale :
Epidemiology, 1990, 1, (3), 195-200
Résumé :
ENGLISH :
Recreational drug (marijuana, lysergic acid diethylamide or LSD, speed, cocaine, and "other") exposures of women with primary infertility were compared with those of a matched control group of women with proven fertility. Women who reported smoking marijuana had a slightly elevated risk for infertility due to an ovulatory abnormality (RR = 1.7, 95% CI = 1.0 to 3.0). The risk was greatest among women who had used marijuana within one year of trying to become pregnant (RR = 2.1, 95% CI = 1.1 to 4.0). No consistent frequency or duration of use effects could be demonstrated, and the risk was confined to low-frequency users. Risks associated with the use of other drugs were not elevated. The risk of infertility from a tubal abnormality associated with cocaine use was greatly increased (RR = 11.1, 95% CI = 1.7 to 70.8). Our results are consistent with animal studies suggesting that smoking marijuana may cause a transient disruption of ovulatory function. The possibility that cocaine exposure influences the development of tubal infertility needs further investigation. (Author' s abstract)
Affiliation :
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98104
Etats-Unis. United States.
Etats-Unis. United States.
Cote :
A03148