Historique
Article de Périodique
A prospective study of the effects of female and male marijuana use on in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT) outcomes (2006)
Auteur(s) :
KLONOFF-COHEN, H. S. ;
NATARAJAN L. ;
CHEN, R. V.
Année
2006
Page(s) :
369-376
Langue(s) :
Anglais
Refs biblio. :
27
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PAT (Pathologie organique / Organic pathology)
Thésaurus mots-clés
ETUDE PROSPECTIVE
;
CANNABIS
;
REPRODUCTION
;
GROSSESSE
;
SEXE FEMININ
;
SEXE MASCULIN
Thésaurus géographique
ETATS-UNIS
Résumé :
OBJECTIVE: This study was undertaken to examine whether marijuana use affects in vitro fertilization and gamete intrafallopian transfer (IVF/GIFT). STUDY DESIGN: Prospective study of 221 IVF/GIFT couples. RESULTS: Amount of lifetime heavy marijuana use adversely affected IVF/GIFT. Women smoking more than 90 times in their lifetime had 27% fewer oocytes retrieved (P = .03) and 1 fewer embryo transferred (P < .05). Women smoking marijuana more than 10 times in their lifetime had infants 17% (P = .01) smaller at birth. If men smoked marijuana 11 to 90 times in their lifetime, there was a 15% decrease in infant birth weight (P = .03); if this increased to more than 90 times, there was a 23% decrease (P = .01). Timing also played a role. Women smoking marijuana 1 year before IVF/GIFT had 25% fewer oocytes retrieved (P = .03), whereas couples had 28% (P = .04) fewer oocytes fertilized. Women and men who smoked in the past 15 years, had 12% (P = .04) and 16% (P = .03) smaller infants, respectively. CONCLUSION: Both timing and amount of marijuana use negatively affected IVF/GIFT. (Author' s abstract)
Affiliation :
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA
Etats-Unis. United States.
Etats-Unis. United States.
Cote :
A03161