Historique
Périodique
Drug use and medication adherence among HIV-1 infected individuals
(Usage de drogue et compliance chez des individus infectés par le VIH-1.)
Auteur(s) :
HINKIN, C. H. ;
BARCLAY, T. R. ;
CASTELLON, S. A. ;
LEVINE, A. J. ;
DURVASULA R. S. ;
MARION, S. D. ;
MYERS, H. F. ;
LONGSHORE, D.
Année
2007
Page(s) :
185-194
Langue(s) :
Français
Refs biblio. :
58
Domaine :
Drogues illicites / Illicit drugs
Discipline :
MAL (Maladies infectieuses / Infectious diseases)
Thésaurus mots-clés
VIH
;
INFECTION
;
SIDA
;
OBSERVANCE DU TRAITEMENT
;
METHAMPHETAMINE
;
COCAINE
;
ETUDE LONGITUDINALE
Thésaurus géographique
ETATS-UNIS
Note générale :
AIDS and Behavior, 2007, 11, (2), 185-194
Résumé :
ENGLISH :
This longitudinal study examined the impact of drug use and abuse on medication adherence among 150 HIV-infected individuals, 102 who tested urinalysis positive for recent illicit drug use. Medication adherence was tracked over a 6-month period using an electronic monitoring device (MEMS caps). Over the 6-month study drug-positive participants demonstrated significantly worse medication adherence than did drug-negative participants (63 vs. 79%, respectively). Logistic regression revealed that drug use was associated with over a fourfold greater risk of adherence failure. Stimulant users were at greatest risk for poor adherence. Based upon within-participants analyses comparing 3-day adherence rates when actively using versus not using drugs, this appears to be more a function of state rather than trait. These data suggest that it is the acute effects of intoxication, rather than stable features that may be characteristic of the drug-using populace, which leads to difficulties with medication adherence. (Author' s abstract)
Affiliation :
David Geffen School of Medicine, University of California at Los Angeles, 760 Westwood Plaza, Room C8-747, Los Angeles, CA 90024. Email : chinkin@ucla.edu
Etats-Unis. United States.
Etats-Unis. United States.
Cote :
A03195