Article de Périodique
Patterns of alcohol drinking and all-cause mortality: results from a large-scale population-based cohort study in Japan (2007)
Auteur(s) :
MARUGAME, T. ;
YAMAMOTO, S. ;
YOSHIMI, I. ;
SOBUE, T. ;
INOUE, M. ;
TSUGANE, S. ;
JAPAN PUBLIC HEALTH CENTER-BASED PROSPECTIVE STUDY GROUP
Année
2007
Page(s) :
1039-1046
Langue(s) :
Anglais
Refs biblio. :
23
Domaine :
Alcool / Alcohol
Discipline :
EPI (Epidémiologie / Epidemiology)
Thésaurus mots-clés
ALCOOL
;
TYPE D'USAGE
;
MORTALITE
;
ETUDE PROSPECTIVE
;
COHORTE
;
EPIDEMIOLOGIE DESCRIPTIVE
Thésaurus géographique
JAPON
Résumé :
To evaluate the hypothesis that, in terms of all-cause death, drinking alcohol 1-4 days per week is less harmful than daily (5-7 days/week) drinking of the same quantity of alcohol, a prospective cohort study using a self-administered questionnaire was conducted in Japan between 1990 and 2003 of 88,746 subjects (41,702 men and 47,044 women) aged 40-69 years at baseline. Among male regular drinkers consuming alcohol more than 1 day per week, light drinkers (<300 g/week) showed no increase in all-cause mortality irrespective of frequency of alcohol intake. Heavy drinkers (>= 300 g/week), however, showed an increased risk of all-cause mortality among those who consumed alcohol 5-7 days per week, while no obvious increase was observed among those who consumed alcohol less than 4 days per week. Hazard ratios for drinkers who consumed alcohol 5-7 days per week were 1.29 (95% confidence interval: 1.12, 1.50) for 300-449 g per week and 1.55 (95% confidence interval: 1.32, 1.81) for >= 450 g per week when compared with those for occasional drinkers who consumed alcohol 1-3 days per month. These findings support the Japanese social belief that "liver holidays," abstaining from alcohol for more than 2 days per week, are important for heavy drinkers.
Affiliation :
Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
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