Historique
Article de Périodique
Crack whips the heart: a review of the cardiovascular toxicity of cocaine (2007)
(Le crack fouette le coeur : revue de la littérature sur la toxicité cardiovasculaire de la cocaïne.)
Auteur(s) :
AFONSO, L. ;
MOHAMMAD T. ;
THATAI D.
Année
2007
Page(s) :
1040-1043
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Refs biblio. :
30
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PAT (Pathologie organique / Organic pathology)
Thésaurus mots-clés
COCAINE
;
PHYSIOLOGIE
;
CRACK
;
COEUR
;
TOXICITE
;
APPAREIL CARDIOVASCULAIRE
;
PATHOLOGIE
;
MORBIDITE
Note générale :
American Journal of Cardiology, 2007, 100, (6), 1040-1043
Résumé :
Cocaine is an extremely powerful reinforcing psychostimulant with highly addictive properties. Over the last few decades, cocaine addiction has attained epidemic proportions in North America, imposing a tremendous burden on society and the health care system. The cardiovascular complications of cocaine abuse are adrenergic mediated and range from cocaine-associated acute coronary syndromes to aortic dissection and sudden cardiac death. Concomitant alcohol and cigarette smoking exacerbate the cardiotoxicity of cocaine. This contemporary review discusses the spectrum of cardiac complications arising from cocaine use, operant pathophysiologic mechanisms and controversies surrounding the pharmacotherapy of cocaine-associated acute coronary syndromes.
Affiliation :
Division of Cardiology, Wayne State University, Detroit, Michigan.
Etats-Unis. United States.
Etats-Unis. United States.
Cote :
A03462