Historique
Article de Périodique
Simple method for revealing of false negative results of urine morphine caused by adulterants (2008)
(Une méthode simple pour révéler les faux résultats négatifs de la morphine dans l'urine causés par des adultérants.)
Auteur(s) :
HEDAYATI M. ;
TAJIC A. ;
DANESHPOUR M. S. ;
KAZEMI, A.
Année
2008
Page(s) :
319-324
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
MORPHINE
;
URINE
;
ADULTERANT
;
DEPISTAGE
;
TEST
;
ANALYSE CHIMIQUE
Thésaurus géographique
IRAN
Note générale :
Journal of Substance Use, 2008, 13, (5), 319-324
Résumé :
ENGLISH :
Aims: The detection of false negative results of urine morphine test caused by adulterants was the main goal of this study. Design/setting: Screening test for urine morphine check was done by two methods of immunochromatography rapid tests and the positive results confirmation was done by thin layer chromatography TLC. Participants: Urine samples that were referred to the Military Laboratory Science Research Center were used in this study. Intervention: Sodium chloride, vinegar, lemon juice, nitrites, hydrogen peroxide, bleach, and pH and gravity effects were consider as common adulterants in the urine morphine check. Measurements: Urine was checked for the presence and absence of the above-mentioned adulterants in urine samples. Finding: The study data showed that test performance using the two methods of analysis, using a presence and absence threshold amount of morphine (300 ng/ml), showed a 100% sensitivity for revealing false negative results due to interference with adulterants. Conclusion: Urine morphine test in double format, with and without threshold amount of morphine, can reveal adulterant interference and prevent false negative reporting. This strategy will be effective in detecting false negatives in urine samples contaminated with adulterants. (Author' s abstract)
Affiliation :
Iran. Iran.
Cote :
Abonnement