Historique
Article de Périodique
Drugs of abuse, opiates (1990)
(Opiacés)
Auteur(s) :
LING, W. ;
WESSON, D. R.
Année
1990
Page(s) :
565-572
Langue(s) :
Anglais
Refs biblio. :
22
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Note générale :
Western Journal of Medicine, 1990, 152, (5), 565-572
Résumé :
FRANÇAIS :
Le sevrage d'un sujet opio-dépendant requière très généralement l'usage de médicaments facilitant le deuil physique de la drogue (méthadone en cure courte, clonidine) ou visant à empêcher le sujet de reprendre son comportement toxicomaniaque par la mise en place d'un traitement de maintenance (méthadone, acétate de lévométhadol, naltrexone, buprénorphine).
ENGLISH:
Treating opiate-dependent patients can be difficult for many physicians because the patients' life-styles, values, and beliefs differ from those of the physicians. Primary care physicians, however, are often involved in the treatment of the medical complications of opiate abuse, and physicians must often manage a patient's opiate dependence until appropriate referral to a drug abuse treatment program can be arranged. Treatment is guided by an understanding of the patient's addictive disease, for which there are specific diagnostic criteria, and an understanding of the pharmacology of opiates of abuse and the medications used in treating opiate dependence. The opiate agonist, methadone, is useful for both detoxification and maintenance. The opiate antagonist, naloxone, is the treatment of choice for opiate overdose, and naltrexone, also an opiate antagonist, is a useful adjunct in subgroups of opiate-dependent patients for preventing relapse. New medications for the treatment of opiate dependence are being developed.
Le sevrage d'un sujet opio-dépendant requière très généralement l'usage de médicaments facilitant le deuil physique de la drogue (méthadone en cure courte, clonidine) ou visant à empêcher le sujet de reprendre son comportement toxicomaniaque par la mise en place d'un traitement de maintenance (méthadone, acétate de lévométhadol, naltrexone, buprénorphine).
ENGLISH:
Treating opiate-dependent patients can be difficult for many physicians because the patients' life-styles, values, and beliefs differ from those of the physicians. Primary care physicians, however, are often involved in the treatment of the medical complications of opiate abuse, and physicians must often manage a patient's opiate dependence until appropriate referral to a drug abuse treatment program can be arranged. Treatment is guided by an understanding of the patient's addictive disease, for which there are specific diagnostic criteria, and an understanding of the pharmacology of opiates of abuse and the medications used in treating opiate dependence. The opiate agonist, methadone, is useful for both detoxification and maintenance. The opiate antagonist, naloxone, is the treatment of choice for opiate overdose, and naltrexone, also an opiate antagonist, is a useful adjunct in subgroups of opiate-dependent patients for preventing relapse. New medications for the treatment of opiate dependence are being developed.
Affiliation :
8447 Wilshire Blvd, Ste 409, Beverly Hills, CA 90211
Etats-Unis. United States.
Etats-Unis. United States.