Historique
Chapitre
The search for cofactors in aids, including an analysis of the association of nitrite inhalant abuse and Kaposi's sarcoma
(Recherche des co-facteurs du sida : relation entre abus de solvants nitrés et sarcome de Kaposi)
Auteur(s) :
HAVERKOS H. W.
Année
1990
Langue(s) :
Anglais
Refs biblio. :
32
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PAT (Pathologie organique / Organic pathology)
Note générale :
In : Alcohol, Immunomodulation and Aids, p. 93-102, Alan R. Liss, 1990
Résumé :
FRANÇAIS :
Le sarcome de Kaposi est une des pathologies liées à l'infection par le VIH. Des études épidémiologiques ont suggéré que l'abus de solvants nitrés, cancérigènes, favoriserait le développement de la maladie de Kaposi.
ENGLISH :
The identification of cofactors in Aids is a challenging scientific task. There is sufficient evidence to suggest the existence of a cofactor in KS in Aids. Nitrite inhalants remain a leading candidate to be the KS cofactor. Until more is known to document or refute this specific virus-drug interaction hypothesis in the pathogenesis of KS in Aids, clinicians should encourage their patients to avoid use of nitrite inhalants. (Extract from author's abstract)
Le sarcome de Kaposi est une des pathologies liées à l'infection par le VIH. Des études épidémiologiques ont suggéré que l'abus de solvants nitrés, cancérigènes, favoriserait le développement de la maladie de Kaposi.
ENGLISH :
The identification of cofactors in Aids is a challenging scientific task. There is sufficient evidence to suggest the existence of a cofactor in KS in Aids. Nitrite inhalants remain a leading candidate to be the KS cofactor. Until more is known to document or refute this specific virus-drug interaction hypothesis in the pathogenesis of KS in Aids, clinicians should encourage their patients to avoid use of nitrite inhalants. (Extract from author's abstract)
Affiliation :
Clin. Med. Branch, Div. Clin. Res., NIDA, Rockville, MD, 20857
Etats-Unis. United States.
Etats-Unis. United States.