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Clonidine versus long and short-term methadone aided withdrawal from opiates : an uncontrolled comparison
(Sevrage des opiacés sous clonidine versus méthadone à long et court-terme : une comparaison à vérifier)
Auteur(s) :
KASVIKIS Y. ;
BRADLEY, B. ;
GOSSOP, M. ;
GRIFFITHS, P. ;
MARKS, I.
Année
1990
Langue(s) :
Anglais
ISBN :
0020-773X
Refs biblio. :
14
Domaine :
Drogues illicites / Illicit drugs
Note générale :
International Journal of the Addictions, 1990, 25, (10), 1169-1178
Résumé :
FRANÇAIS :
Etude statistique sur un petit groupe d'opiomanes en cure de désintoxication concernant le syndrome de sevrage. Avantages et inconvénients du remplacement de la méthadone par la clonidine ; les auteurs insistent sur la nécessité de poursuivre cette recherche, car les premiers résultats semblent encourageants (doses minimes, effets secondaires réduits, etc...)
ENGLISH :
Twelve heroin addicts and one methadone addict began withdrawal from street opiates, under clonidine cover, in a general psychiatric ward. Ten of them completed it within 6 days. Clonidine doses used were lower than in similar studies and all patients were alert and mobile troughout withdrawal. Two other groups of opiate addicts, of similar age and sex, were withdrawn on standard methadone regimens. Clonidine and methadone withdrawal had similar acceptability and attrition rates. Self-reports of subjective discomfort were higher in the clonidine group without affecting compliance with treatment. Withdrawal under clonidine cover deserves further study, in view of the need for postwithdrawal treatment to prevent relapse to opiate use. (Author's abstract)
Etude statistique sur un petit groupe d'opiomanes en cure de désintoxication concernant le syndrome de sevrage. Avantages et inconvénients du remplacement de la méthadone par la clonidine ; les auteurs insistent sur la nécessité de poursuivre cette recherche, car les premiers résultats semblent encourageants (doses minimes, effets secondaires réduits, etc...)
ENGLISH :
Twelve heroin addicts and one methadone addict began withdrawal from street opiates, under clonidine cover, in a general psychiatric ward. Ten of them completed it within 6 days. Clonidine doses used were lower than in similar studies and all patients were alert and mobile troughout withdrawal. Two other groups of opiate addicts, of similar age and sex, were withdrawn on standard methadone regimens. Clonidine and methadone withdrawal had similar acceptability and attrition rates. Self-reports of subjective discomfort were higher in the clonidine group without affecting compliance with treatment. Withdrawal under clonidine cover deserves further study, in view of the need for postwithdrawal treatment to prevent relapse to opiate use. (Author's abstract)
Affiliation :
Behav. Treatment Unit, 9 Zaimi st., Athens TK 10682
Grèce. Greece.
Grèce. Greece.