Historique
Article de Périodique
Benzodiazépines: abuse and new use (1991)
(Benzodiazépines : abus et usages nouveaux)
Auteur(s) :
WARNEKE L.B.
Année
1991
Page(s) :
194-205
Langue(s) :
Anglais
Refs biblio. :
126
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Résumé :
FRANÇAIS :
Les benzodiazépines sont des produits dont le mode d'action et les propriétés pharmacologiques, rappelés ici, sont maintenant relativement éclaircis. Elles peuvent induire des manifestations de dépendance, très rares si leur usage est bien codifié et de toute façon peu péjoratives, et gagnent en intérêt dans la mesure où le champ de leurs indications s'est récemment élargi : attaques de panique, manies, catatonie, certaines manifestations psychotiques, douleurs, épilepsie.
ENGLISH :
Both abuse and new uses for benzodiazepines are reviewed. The pharmacology of benzodiazepines is summarized and statistics regarding their general use are given. The question of benzodiazepine abuse is reviewed in some detail and the question of rebound, recurrence of symptoms and physiological withdrawal is differentiated. Benzodiazepines are regarded as a very safe class of drugs and the abuse potential is felt to be negligible provided that they are prescribed for appropriate conditions and monitored carefully. The dangers of alternatives to benzodiazepines such as alcohol or barbiturates is emphasized. New uses for benzodiazepines are reviewed including the use of benzodiazepines in panic disorder, as well as an adjunct in the therapy of mania and some psychotic states. Rational prescribing of benzodiazepines is encouraged and the attitude that these are dangerous and addictive drugs is discouraged and put into perspective.
Les benzodiazépines sont des produits dont le mode d'action et les propriétés pharmacologiques, rappelés ici, sont maintenant relativement éclaircis. Elles peuvent induire des manifestations de dépendance, très rares si leur usage est bien codifié et de toute façon peu péjoratives, et gagnent en intérêt dans la mesure où le champ de leurs indications s'est récemment élargi : attaques de panique, manies, catatonie, certaines manifestations psychotiques, douleurs, épilepsie.
ENGLISH :
Both abuse and new uses for benzodiazepines are reviewed. The pharmacology of benzodiazepines is summarized and statistics regarding their general use are given. The question of benzodiazepine abuse is reviewed in some detail and the question of rebound, recurrence of symptoms and physiological withdrawal is differentiated. Benzodiazepines are regarded as a very safe class of drugs and the abuse potential is felt to be negligible provided that they are prescribed for appropriate conditions and monitored carefully. The dangers of alternatives to benzodiazepines such as alcohol or barbiturates is emphasized. New uses for benzodiazepines are reviewed including the use of benzodiazepines in panic disorder, as well as an adjunct in the therapy of mania and some psychotic states. Rational prescribing of benzodiazepines is encouraged and the attitude that these are dangerous and addictive drugs is discouraged and put into perspective.
Affiliation :
Dept Psychiatr., Grey Nuns Hosp., Edmonton, AB
Canada
Canada