Historique
Périodique
Treatment of heroin addicts using buprenorphine
(Traitement des héroïnomanes par la buprénorphine)
Auteur(s) :
KOSTEN, T. R. ;
MORGAN, C. ;
KLEBER, H. D.
Année
1991
Langue(s) :
Anglais
ISBN :
0095-2990
Refs biblio. :
31
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
DESINTOXICATION
;
HEROINE
;
METHADONE
;
BUPRENORPHINE
;
NALTREXONE
;
CURE DE DESINTOXICATION
;
SYNDROME DE SEVRAGE
Note générale :
American Journal of Drug and Alcohol Abuse, 1991, 17, (2), 119-128
Résumé :
FRANÇAIS :
On décrit un protocole de traitement de trente neuf héroïnomanes par la buprénorphine. La stratégie adoptée vise à introduire précocement la buprénorphine pour faciliter le passage des agonistes opioides aux antagonistes (naltrexone), en trois étapes. L'évaluation de l'efficacité de ce protocole est globalement positive, en particulier concernant l'adoucissement du syndrome de sevrage.
ENGLISH :
Thirty-nine opioid-dependent oupatients were treated with the partial agonist buprenorphine at 2 to 6 mg / day for 1 month. Treatment retention was good (72%), and illicit opioid use decreased from 50% overall to 17% for those who remained in treatment. Precipitated withdrawal symptoms were mild and related to dose of buprenorphine. At the end of this month, 28 subjects were abruptly discontinued from buprenorphine and given the antagonist naltrexone. Withdrawal symptoms from buprenorphine were quite mild. (Extract from author's abstract)
On décrit un protocole de traitement de trente neuf héroïnomanes par la buprénorphine. La stratégie adoptée vise à introduire précocement la buprénorphine pour faciliter le passage des agonistes opioides aux antagonistes (naltrexone), en trois étapes. L'évaluation de l'efficacité de ce protocole est globalement positive, en particulier concernant l'adoucissement du syndrome de sevrage.
ENGLISH :
Thirty-nine opioid-dependent oupatients were treated with the partial agonist buprenorphine at 2 to 6 mg / day for 1 month. Treatment retention was good (72%), and illicit opioid use decreased from 50% overall to 17% for those who remained in treatment. Precipitated withdrawal symptoms were mild and related to dose of buprenorphine. At the end of this month, 28 subjects were abruptly discontinued from buprenorphine and given the antagonist naltrexone. Withdrawal symptoms from buprenorphine were quite mild. (Extract from author's abstract)
Affiliation :
Subst. Abuse Treatment Unit, Psychiat. Dept, Connecticut Ment. Hlth Ctr, Yale Univ. Sch. Med., New Haven, CF 06519
Etats-Unis. United States.
Etats-Unis. United States.