Historique
Périodique
Observations on increased CPK levels in "asymptomatic" cocaine abusers
(Augmentation du niveau des CPK chez les cocaïnomanes asymptomatiques)
Auteur(s) :
WARRIAN W.G. ;
HALIKAS J.A. ;
CROSBY, R. D. ;
CARLSON, G. A. ;
CREA F.
Année
1992
Langue(s) :
Anglais
ISBN :
1055-0887
Refs biblio. :
45
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PAT (Pathologie organique / Organic pathology)
Note générale :
Journal of Addictive Diseases, 1992, 11, (4), 83-95
Résumé :
FRANÇAIS :
Une fois éliminée toute cause médicale, on observe chez les consommateurs de cocaïne non traités, une augmentation de la créatine phosphokinase (CPK) plus importante que celle observée chez les consommateurs d'alcool. Le CPK est un marqueur de la rhabdomyolyse, complication fréquente de l'usage de cocaïne.
ENGLISH :
In order to assess increased creatinine phosphokinase (CPK) among medically asymptomatic active crack cocaine abusers, retrospective analysis of daily supervised urine data collected in a 20 day daily visit plus 12 week followup weekly visit study of heavy crack cocaine abusers was performed. With alcohol use instances excluded, a statistically significant relationship between urine cocaine metabolite and elevated CPK was found. When all other possible causes of elevated CPK levels were controlled, crack cocaine use was associated with a significant quantitative effect on CPK level.(Author's abstract)
Une fois éliminée toute cause médicale, on observe chez les consommateurs de cocaïne non traités, une augmentation de la créatine phosphokinase (CPK) plus importante que celle observée chez les consommateurs d'alcool. Le CPK est un marqueur de la rhabdomyolyse, complication fréquente de l'usage de cocaïne.
ENGLISH :
In order to assess increased creatinine phosphokinase (CPK) among medically asymptomatic active crack cocaine abusers, retrospective analysis of daily supervised urine data collected in a 20 day daily visit plus 12 week followup weekly visit study of heavy crack cocaine abusers was performed. With alcohol use instances excluded, a statistically significant relationship between urine cocaine metabolite and elevated CPK was found. When all other possible causes of elevated CPK levels were controlled, crack cocaine use was associated with a significant quantitative effect on CPK level.(Author's abstract)
Affiliation :
Univ. Minnesota, Box 393 UMHC, Minneapolis, MN 55455
Etats-Unis. United States.
Etats-Unis. United States.