Historique
Périodique
The misuse of buprenorphine and a buprenorphine-naloxone combination in Wellington, New Zealand
(Détournement de buprénorphine et de l'association buphrénorphine/naloxone à Wellington, Nouvelle Zélande)
Auteur(s) :
ROBINSON, G. M. ;
DUKES P.D. ;
ROBINSON, B. J. ;
COOKE, R. R. ;
MAHONEY G.N.
Année
1993
Langue(s) :
Anglais
ISBN :
0376-8716
Refs biblio. :
30
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
OPIACES
;
BUPRENORPHINE
;
NALOXONE
;
MESUSAGE
;
SEVRAGE
;
TRAITEMENT
;
VOIE INTRAVEINEUSE
Note générale :
Drug and Alcohol Dependence, 1993, 33, (1), 81-86
Résumé :
FRANÇAIS :
Deux enquêtes effectuées chez les patients consommateurs d'opiacés d'un hôpital de Wellington, montrent que la buprénorphine, donnée comme médicament de substitution est détournée par 81% d'entre-eux. L'association buprénorphine/naloxone, bien qu'ayant un potentiel d'abus plus faible, est également détournée par 57% des usagers.
ENGLISH :
Two surveys of 12 months duration were undertaken on opioid users presenting to the Wellington Alcohol and Drug Centre before and after the introduction of a combination buprenorphine 0.2mg - naloxone 0.17mg tablet (Bu-Nx), which was launched in 1991 in the hope of reducing intravenous misuse. There was considerable intravenous (i.v.) misuse of buprenorphine 0.2mg tablets (Bu) in 1990 with self-reports of misuse in 81% of the patients over the 4 weeks prior to presentation, and 65% of the patients had buprenorphine in their urine. In the repeat survey 57% reported misuse of the Bu-Nx combination over the previous 4 weeks, and 43% had buprenorphine = naloxone detected in their urine. The combination product may have less misuse potential than buprenorphine alone, but it remains a preparation, in the dosages employed, that it intravenously misused. (From author's abstract)
Deux enquêtes effectuées chez les patients consommateurs d'opiacés d'un hôpital de Wellington, montrent que la buprénorphine, donnée comme médicament de substitution est détournée par 81% d'entre-eux. L'association buprénorphine/naloxone, bien qu'ayant un potentiel d'abus plus faible, est également détournée par 57% des usagers.
ENGLISH :
Two surveys of 12 months duration were undertaken on opioid users presenting to the Wellington Alcohol and Drug Centre before and after the introduction of a combination buprenorphine 0.2mg - naloxone 0.17mg tablet (Bu-Nx), which was launched in 1991 in the hope of reducing intravenous misuse. There was considerable intravenous (i.v.) misuse of buprenorphine 0.2mg tablets (Bu) in 1990 with self-reports of misuse in 81% of the patients over the 4 weeks prior to presentation, and 65% of the patients had buprenorphine in their urine. In the repeat survey 57% reported misuse of the Bu-Nx combination over the previous 4 weeks, and 43% had buprenorphine = naloxone detected in their urine. The combination product may have less misuse potential than buprenorphine alone, but it remains a preparation, in the dosages employed, that it intravenously misused. (From author's abstract)
Affiliation :
Alcoh. Drug Ctr., Wellington Hosp., Private Bag, Wellington
Nouvelle Zélande. New Zealand.
Nouvelle Zélande. New Zealand.