Historique
Périodique
Cocaine use and other suspected risk factors for obsessive-compulsive disorder : a prospective study with data from the epidemiologic catchment area surveys
(Usage de cocaïne et autres facteurs de risque impliqués dans les troubles obsessionnels : étude prospective à partir des données des programmes ECA (Epidemiological Catchment Area))
Auteur(s) :
CRUM, R. M. ;
ANTHONY, J. C.
Année
1993
Langue(s) :
Anglais
ISBN :
0376-8716
Refs biblio. :
43
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus mots-clés
COCAINE
;
CONSOMMATION
;
PSYCHIATRIE
;
PATHOLOGIE
;
DIAGNOSTIC
;
FACTEUR DE RISQUE
Note générale :
Drug and Alcohol Dependence, 1993, 31, 281-295
Résumé :
FRANÇAIS :
A partir d'études englobant 18572 participants, on peut mettre en évidence que les usagers de cocaïne ont un risque accru de troubles obsessionnels. Presque tous sont cependant polytoxicomanes, ce qui ne permet pas d'affirmer que ce risque est totalement lié à la cocaine.
ENGLISH :
Using prospectively gathered epidemiologic data, we sought to estimate the degree to which the risk of obsessive-compulsive disorder might be elevated among adults actively using cocaine, with and without illicit use of marijuana or other controlled substances. Subjects actively using cocaine and also marijuana were found to be at increased risk for OCD. Under the conditional model, the estimated relative risk was 7.2 (P=0.03), while the value from unconditional regression was 4.1 (P=0.01). Active users of cocaine almost always were active users of marijuana or some other controlled substance, so it was not possible to estimate a relative risk value for subjects using cocaine only. Nonetheless, if replicated, this epidemiologic test of the cocaine-OCD hypothesis warrants attention in laboratory and clinical research, as do other suspected risk factors identified in the study, including sex (being female), employment status (not working for pay) and a prior history of distinct psychiatric disorders such as alcohol dependence, affective disorders and phobic disorders. (Extract from author's abstract)
A partir d'études englobant 18572 participants, on peut mettre en évidence que les usagers de cocaïne ont un risque accru de troubles obsessionnels. Presque tous sont cependant polytoxicomanes, ce qui ne permet pas d'affirmer que ce risque est totalement lié à la cocaine.
ENGLISH :
Using prospectively gathered epidemiologic data, we sought to estimate the degree to which the risk of obsessive-compulsive disorder might be elevated among adults actively using cocaine, with and without illicit use of marijuana or other controlled substances. Subjects actively using cocaine and also marijuana were found to be at increased risk for OCD. Under the conditional model, the estimated relative risk was 7.2 (P=0.03), while the value from unconditional regression was 4.1 (P=0.01). Active users of cocaine almost always were active users of marijuana or some other controlled substance, so it was not possible to estimate a relative risk value for subjects using cocaine only. Nonetheless, if replicated, this epidemiologic test of the cocaine-OCD hypothesis warrants attention in laboratory and clinical research, as do other suspected risk factors identified in the study, including sex (being female), employment status (not working for pay) and a prior history of distinct psychiatric disorders such as alcohol dependence, affective disorders and phobic disorders. (Extract from author's abstract)
Affiliation :
Sch. Hygiène Publ. Hlth, J. Hopkins Univ., 264 North Broadway, Baltimore MD 21205
Etats-Unis. United States.
Etats-Unis. United States.