Historique
Périodique
Opiod miosis : effects of lighting intensity and monocular and binocular exposure
(Myosis aux opiacés : effets de l'intensité lumineuse et d'une exposition monoculaire et binoculaire)
Auteur(s) :
WEINHOLD L.L. ;
BIGELOW, G. E.
Année
1993
Langue(s) :
Anglais
ISBN :
0376-8716
Refs biblio. :
13
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PAT (Pathologie organique / Organic pathology)
Note générale :
Drug and Alcohol Dependence, 1993, 31, 177-181
Résumé :
FRANÇAIS :
Ce travail étudie l'effet des opiacés sur le diamètre pupillaire et celui d'intensités lumineuses variables. La myosis consécutive à l'usage d'opiacés, serait mieux détectée 90 min après l'administration des drogues et sous une intensité lumineuse moyenne.
ENGLISH :
This study is the first systematic examination and quantitative characterization of the effects of lighting intensity and exposure on opioid miosis. Seven patients received their usual daily dose of methadone (50-60 mg p.o.). Reflected light intensities were manipulated among 4, 16, 40, 80, 160, 240 foot-lamberts (fl). Peak methadone miosis was best detected under moderately dim interior lighting (4, 16 fl) 90 min after methadone. Pupil diameters were systematically larger with one eye closed than with both eyes open and the average differences was 0.35 mm. Pupil diameter decreased 1.0 mm with each log unit increase in lighting intensity.
Ce travail étudie l'effet des opiacés sur le diamètre pupillaire et celui d'intensités lumineuses variables. La myosis consécutive à l'usage d'opiacés, serait mieux détectée 90 min après l'administration des drogues et sous une intensité lumineuse moyenne.
ENGLISH :
This study is the first systematic examination and quantitative characterization of the effects of lighting intensity and exposure on opioid miosis. Seven patients received their usual daily dose of methadone (50-60 mg p.o.). Reflected light intensities were manipulated among 4, 16, 40, 80, 160, 240 foot-lamberts (fl). Peak methadone miosis was best detected under moderately dim interior lighting (4, 16 fl) 90 min after methadone. Pupil diameters were systematically larger with one eye closed than with both eyes open and the average differences was 0.35 mm. Pupil diameter decreased 1.0 mm with each log unit increase in lighting intensity.
Affiliation :
NIDA, Addict. Res. Ctr., PO Box 5180, Baltimore, MD 21 224
Etats-Unis. United States.
Etats-Unis. United States.