Historique
Périodique
Early development of infants exposed to drugs prenatally
(Développement précoce des enfants ayant subi une exposition prénatale aux drogues.)
Auteur(s) :
EYLER F. D. ;
BEHNKE, M.
Année
1999
Page(s) :
107-150
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
ISBN :
0095-5108
Refs biblio. :
146
Domaine :
Plusieurs produits / Several products
Thésaurus mots-clés
ENFANT D'USAGER
;
ALCOOL
;
TABAC
;
CANNABIS
;
OPIACES
;
COCAINE
;
TOXICITE
;
CERVEAU
;
CROISSANCE
;
COMPORTEMENT
;
RECHERCHE
Note générale :
Clinics in Perinatology, 1999, 107, 107-150
Note de contenu :
tabl.
Résumé :
ENGLISH :
Following the immediate postpartum period and any medical sequelae or abstinence effects that are related to prenatal drug exposure, the question remains about the possibility of lasting neurodevelopmental consequences. This article summarizes the peer-reviewed literature published during last two decades, examining representative studies of the developmental outcome of drug-exposed infants during the first 2 years of life (see the article by Tronick for more long-term follow-up). The most commonly used drugs of abuse are reviewed, that is, opioids (primarily heroin and methadone), cocaine, marijuana, alcohol, and tobacco. Limitations of findings are discussed with respect to methodologic issues and the need for future research. When a series of studies have been published in an area, the more recent publications are examined (especially if samples are larger, controls are added, or cohorts are older). A review of human studies of prenatal drug exposure by drug group is somewhat arbitrary because it is rare for women to use only one type of drug during pregnancy. Findings of the effects of a specific drug are most reliable and generalizable when studies have been designed to enroll prospectively a random or representative sample of users of that specific drug. Therefore, the following sections review studies designed to investigate a specific drug, assuming that information is available. Any developmental outcome significantly related to other drugs emphasized in this article is described. (Author' s abstract)
Affiliation :
Dprt of Pediatrics, Div. of Neonatology, Univ. of Florida, Gaisneville, Florida
Etats-Unis. United States.
Etats-Unis. United States.