Historique
Article de Périodique
Effect of cannabis use on cognitive functions and driving ability (1999)
(Effets du cannabis sur les fonctions cognitives et l'aptitude à la conduite de véhicule)
Auteur(s) :
KURZTHALERT, I. ;
HUMMER, M. ;
MILLER, C. ;
SPERNER-UNTERWEGER, B. ;
GÜNTHER, V. ;
WECHDORN, H. ;
BATTISTA, H. J. ;
FLEISCHHACKER W. W.
Année
1999
Page(s) :
395-399
Langue(s) :
Anglais
Refs biblio. :
24
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Note générale :
Journal of Clinical Psychiatry, 1999, 60, (6), 395-399
Résumé :
FRANÇAIS :
Une étude en double aveugle, contre placébo, a été menée auprès de 60 volontaires sains (test de dépistage urinaire de drogues négatif). Le premier jour, un examen physique, des tests psychologiques de la mémoire visuelle et verbale, et des performances de perception cognitives ont permis de collecter les données de base de l'étude. Le deuxième jour, les sujets ont reçu 290 microg/kg de tétrahydrocannabinol. 15 min après, les évaluations physiques et psychologiques ont été faites, puis renouvelées 24h plus tard. Les résultats suggèrent que la perception de la vitesse de conduite ainsi que la précision sont diminuées après consommation de cannabis.
ENGLISH :
Background: Neither experimental nor epi demiologic approaches have so far given defini tive answers to the question of the potential ef fect of cannabis on driving ability.
Method: To shed more light on this topic, we conducted a placebo-controlled double-blind study including 60 healthy volunteers (a nega tive urine drug screening test was prerequisite). On the first day, baseline data were obtained from a physical examination and a psychologi cal test battery for the investigation of visual and verbal memory as well as cognitive percep tual performance. On the second day, subjects received a regular cigarette or one containing 290 ug/kg body weight of tetrahydrocannabinol. Physical and psychological assessments were performed immediately (15 minutes) after sub jects smoked their cigarettes, Twenty-four hours later, physical and psychological examinations were repeated.
Results and Conclusion: Our results suggest that perceptual motor speed and accuracy. 2 very important parameters of driving ability, seem to be impaired immediately after cannabis consumption.
Une étude en double aveugle, contre placébo, a été menée auprès de 60 volontaires sains (test de dépistage urinaire de drogues négatif). Le premier jour, un examen physique, des tests psychologiques de la mémoire visuelle et verbale, et des performances de perception cognitives ont permis de collecter les données de base de l'étude. Le deuxième jour, les sujets ont reçu 290 microg/kg de tétrahydrocannabinol. 15 min après, les évaluations physiques et psychologiques ont été faites, puis renouvelées 24h plus tard. Les résultats suggèrent que la perception de la vitesse de conduite ainsi que la précision sont diminuées après consommation de cannabis.
ENGLISH :
Background: Neither experimental nor epi demiologic approaches have so far given defini tive answers to the question of the potential ef fect of cannabis on driving ability.
Method: To shed more light on this topic, we conducted a placebo-controlled double-blind study including 60 healthy volunteers (a nega tive urine drug screening test was prerequisite). On the first day, baseline data were obtained from a physical examination and a psychologi cal test battery for the investigation of visual and verbal memory as well as cognitive percep tual performance. On the second day, subjects received a regular cigarette or one containing 290 ug/kg body weight of tetrahydrocannabinol. Physical and psychological assessments were performed immediately (15 minutes) after sub jects smoked their cigarettes, Twenty-four hours later, physical and psychological examinations were repeated.
Results and Conclusion: Our results suggest that perceptual motor speed and accuracy. 2 very important parameters of driving ability, seem to be impaired immediately after cannabis consumption.
Affiliation :
Dept Biol. Psychiat., Innsbruck Univ. Clin., Innsbruck, Austria