Historique
Périodique
Cardiovascular toxicity after ingestion of "herbal ecstacy"
(Toxicité cardiovasculaire suite à l'ingestion d' "ecstasy" à base de plantes)
Auteur(s) :
ZAHN, K. A. ;
LI, R. L. ;
PURSSELL R. A.
Année
1999
Page(s) :
289-291
Langue(s) :
Anglais
Refs biblio. :
14
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
MDMA-ECSTASY
;
TOXICITE
;
PHARMACOLOGIE
;
BOTANIQUE
;
BRONCHODILATATEURS
;
ETUDE DE CAS
;
APPAREIL CARDIOVASCULAIRE
Note générale :
Journal of Emergency Medecine, 1999, 17, (2), 289-291
Résumé :
FRANÇAIS :
Après ingestion de capsules contenant diverses plantes (gingembre, noix de cola, de muscade...), appelées "herbal ecstasy " ou "Cloud 9" ou "Ultimate Xphoria", un jeune homme de 21 ans a été admis aux urgences pour dysrythmie ventriculaire et hypertension. Ces préparations contiennent souvent de l'éphédrine et de la caféine. L'administration d'antidysrythmique (lidocaïne) et d'hypotenseur (nitroprusside de sodium ou phentolamine) permet la résolution des symptômes. La physiopathologie et l'évolution clinique de la toxicité de l'éphédrine sont présentées.
ENGLISH :
"Herbal Ecstacy" (sic) Is an alternative drug of abuse usually containing both ephedrine and caffeine. Our literature search did not reveal any other reported cases of cardiovascular toxicity related to herbal "drugs of abuse' A case of cardiovascular toxicity following the ingestion of herbal ecstacy is presented. A 21-year-old male presented to the emergency department with an initial blood pressure of 220/110 mmHg and ventricular dysrhythmias after ingesting four capsules of herbal ecstacy. He was treated with lidocaine and sodium nitroprusside, and his symptoms resolved in 9 h. The pathophysiology and clinical course of ephedrine toxicity are discussed. Emergency phy- sicians should consider ephedrine preparations in the differential diagnosis of patients presenting with a sympathomimetic toxidrome. Drugs of abuse containing "herbal" products can produce serious morbidity and mortality. (Author' s abstract)
Après ingestion de capsules contenant diverses plantes (gingembre, noix de cola, de muscade...), appelées "herbal ecstasy " ou "Cloud 9" ou "Ultimate Xphoria", un jeune homme de 21 ans a été admis aux urgences pour dysrythmie ventriculaire et hypertension. Ces préparations contiennent souvent de l'éphédrine et de la caféine. L'administration d'antidysrythmique (lidocaïne) et d'hypotenseur (nitroprusside de sodium ou phentolamine) permet la résolution des symptômes. La physiopathologie et l'évolution clinique de la toxicité de l'éphédrine sont présentées.
ENGLISH :
"Herbal Ecstacy" (sic) Is an alternative drug of abuse usually containing both ephedrine and caffeine. Our literature search did not reveal any other reported cases of cardiovascular toxicity related to herbal "drugs of abuse' A case of cardiovascular toxicity following the ingestion of herbal ecstacy is presented. A 21-year-old male presented to the emergency department with an initial blood pressure of 220/110 mmHg and ventricular dysrhythmias after ingesting four capsules of herbal ecstacy. He was treated with lidocaine and sodium nitroprusside, and his symptoms resolved in 9 h. The pathophysiology and clinical course of ephedrine toxicity are discussed. Emergency phy- sicians should consider ephedrine preparations in the differential diagnosis of patients presenting with a sympathomimetic toxidrome. Drugs of abuse containing "herbal" products can produce serious morbidity and mortality. (Author' s abstract)
Affiliation :
Department Emergency Med., Vancouver General Hosp., 855 W., 12th Avenue, Vancouver, BC, V5Z 1M9
Canada. Canada.
Canada. Canada.