Historique
Périodique
Electroretinogram and cue-elicited craving in withdrawn cocaine-dependent patients: a replication
(Electroretinogramme et syndrome de manque induit par des stimuli de cocaïne chez des patients sevrés de cocaïne : reproduction de résultats)
Auteur(s) :
SMELSON, D. A. ;
ROY, A. ;
ROY, M. ;
TERSHAKOVEC, D. ;
ENGELHART, C. ;
LOSONCZY, M. F.
Année
2001
Page(s) :
391-397
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Note générale :
American Journal of Drug and Alcohol Abuse (The), 2001, 27, (2), 391-397
Résumé :
We previously reported that cocaine-dependent patients with a reduced blue cone b wave electroretinogram (ERG) responses had significantly more cue-elicited craving. Methods: A new series of 21 recently withdrawn cocaine-dependent patients completed a craving questionnaire at baseline and following cue exposure; an ERG was also performed. Results: Cocaine-dependent patients with a blunted ERG blue cone response (<0.5 uN) showed greater increases in craving following cue exposure. When subjects were included from our preliminary study (N=14), these differences became highly significant. Conclusions: Patients with a reduced ERG response may represent a subgroup more vulnerable to cocaine craving and future relapse. (Author's abstract)
Affiliation :
Dept. Veterans Affairs, New Jersey Health Care System, Lyons Campus, Mental Health and Behavioral Sciences Building 143, 151 Knollcroft Road, Lyons, New Jersey 07939-5000
Etats-Unis. United States.
Etats-Unis. United States.