Historique
Périodique
Susceptibility to subsequent episodes of spontaneous recurrence of methamphetamine psychosis
(Prédisposition à des épisodes postérieurs de récurrence spontanée de psychose aux méthamphétamines)
Auteur(s) :
YUI, K. ;
GOTO, K. ;
IKEMOTO, S. ;
NISHIJIMA, K. ;
YOSHINO, T. ;
ISHIGURO, T.
Année
2001
Page(s) :
133-142
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Note générale :
Drug and Alcohol Dependence, 2001, 64, (2), 133-142
Résumé :
We examine susceptibility to subsequent spontaneous recurrences of methamphetamine psychosis (i.e. flashbacks) in 11 flashbackers with a single episode and in nine flashbackers with subsequent episodes. All had undergone frightening stressful experiences during previous MAP use. Mild psychosocial stressors then triggered flashbacks. During flashbacks, the nine flashbackers with subsequent episodes had more markedly increased norepinephrine levels, with slightly increased 3-methoxytyramine levels. The duration of imprisonment in this subgroup approached significantly long levels than in the 11 flashbackers with a single episode. Robust noradrenergic hyperactivity with slightly increased dopamine release may therefore predict subsequent flashbacks. Longer exposure to distressing situations may also contribute to robust noradrenergic hyperactivity. (Author's abstract.)
Affiliation :
Dept. Psychiatr., Jichi Med. Sch., Tochigi 329-0498
Japon. Japan.
Japon. Japan.