Historique
Périodique
Neurobiological causes of addiction
(Les causes neurologiques de l'addiction.)
Auteur(s) :
ERICKSON, C. K. ;
WILCOX, R. E.
Année
2001
Page(s) :
7-22
Langue(s) :
Anglais
Refs biblio. :
9
Domaine :
Plusieurs produits / Several products
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
ETIOLOGIE
;
GENETIQUE
;
NEUROBIOLOGIE
;
BIOSENSIBILISATION
;
RECHUTE
;
TRAITEMENT
Note générale :
Journal of Social Work Practice in the Addictions, 2001, 1, (3), 7-22
Note de contenu :
fig. ; tabl.
Résumé :
ENGLISH :
Neurobiology and molecular genetics are contributing heavily to a new understanding of the causes of chemical dependence ("addiction"). Willful chemical abuse is a problem that continues to produce significant societal costs including accidents, medical expenses, and family suffering. Pathological chemical dependence, on the other hand, is being recognized as a true medical disease that is also devastating, but in different ways. There is strong evidence in animals and humans that chemical dependence involves a dysregulation of the pleasure pathway (the "media] forebrain bundle"), located in the mesolimbic portion of the brain. Dopamine is one of the medial forebrain bundle's major neurotransmitters. In this paper, we provide a research-based model for the causes of chemical dependence and its treatment, and integrate this information with classic Twelve Step treatment programs. (Author' s abstract)
Affiliation :
Addict. Res. Educ. Ctr, Coll. Pharm., Univ. Texas, Austin, TX 78712
Etats-Unis. United States.
Etats-Unis. United States.