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Is craving for heroin and alcohol related to low methadone dosages in methadone maintained patients ?
(Le manque d'héroïne et d'alcool est-il lié à une posologie faible en méthadone chez des patients en traitement de maintenance ?)
Auteur(s) :
LUBRANO S. ;
PACINI, M. ;
GIUNTOLI G. ;
MAREMMANI, I.
Année
2002
Page(s) :
11-18
Langue(s) :
Anglais
Refs biblio. :
18
Domaine :
Drogues illicites / Illicit drugs
Note générale :
Heroin Addiction and Related Clinical Problems, 2002, 4, (2), 11-18
Note de contenu :
tabl.
Résumé :
ENGLISH :
The craving for heroin, alcohol and cocaine of 84 heroin-addicted patients under Methadone Maintenance Treatment have been evaluated to highlight possible craving clusters, and to underline contingent correlations with clinical characteristics such as addiction history, positive symptom distress and methadone dosages. The results show a correlation between methadone dosage and a craving for heroin and alcohol. Patients treated with low dosages of methadone show more psychopathological symptoms and a stronger craving for heroin and alcohol. On this basis, the search for an appropriate methadone dosage should be viewed as crucial to the success of the treatment, because it minimizes alcohol and heroin craving, and reduces the risk of psychopathological symptoms during treatment.
Affiliation :
Dept Psychiat., Neurobiol., Pharmacol. and Biotechnol., Univ. Pisa, Via Roma 67, 56100 Pisa
Italie. Italy.
Italie. Italy.