Historique
Périodique
Correlation between hepatitis C serostatus and methadone dose requirement in 1,163 methadone-maintained patients
(Corrélation entre le statut sérique vis-à-vis de l'hépatite C et la posologie en méthadone chez 1163 patients en traitement de maintenance.)
Auteur(s) :
MAXWELL, S. ;
SHINDERMAN M. S. ;
MINER A. ;
BENNET, A.
Année
2002
Page(s) :
5-9
Langue(s) :
Anglais
Refs biblio. :
22
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
METHADONE
;
TRAITEMENT DE MAINTENANCE
;
POSOLOGIE
;
SEROPOSITIVITE
;
HEPATITE
;
ADAPTATION
Note générale :
Heroin Addiction and Related Clinical Problems, 2002, 4, (2), 5-9
Résumé :
ENGLISH :
Hepatitis C infection is epidemic in intravenous drug users worldwide. This has great impact on opiate-addicted patients. Prevention of infection must depend on treatment of opiate addiction. This report discusses findings from 1,163 methadone- maintained patients tested for hepatitis C infection. The prevalence of HCV seropositivity in IVDU patients was 68%. Seropositive patients required significantly higher doses of methadone (169 mg/d vs. 100 mg/d, p<.05). This difference in dose was independent of duration of addiction and time in treatment. It is suggested that Hepatitis C infection may be associated with metabolic changes that lead to increased methadone requirement. (Author' s abstract)
Affiliation :
Ctr. Addictive Problems, 609 N Wells, Chicago IL 60610
Etats-Unis. United States.
Etats-Unis. United States.