Historique
Périodique
Naltrexone and dysphoria: fact or myth ?
(Naltrexone et dysphorie : réalité ou mythe ?)
Auteur(s) :
MIOTTO, K. ;
McCANN, M. ;
BASCH, J. ;
RAWSON, R. ;
LING, W.
Année
2002
Page(s) :
151-160
Langue(s) :
Anglais
Refs biblio. :
60
Domaine :
Drogues illicites / Illicit drugs
Note générale :
American Journal on Addictions, 2002, 11, (2), 151-160
Résumé :
ENGLISH :
Naltrexone is an opiate antagonist used as a pharmacologic adjuvant for the treatment of opiate and alcohol addiction. It bas been hypothesized that naltrexone blocks the stress-response and well-being effects associated with opioid peptides. This raises the clinical concern that naltrexone may cause opioid, and nicotine studies to delermine if an association between naltrexone and dysphoria exists. These studies did not reveal dyspboria to be a serious side effect produced by naltrexone treatment. Additionals studies to evaluate long-term endocrine effects and antidepressant combination therapy are warranted. (Author' s abstract)
Affiliation :
UCLA Dept Psychiat. Biobehavioral Sci., 760 Westwood Plaza, Los Angeles, CA 90024
Etats-Unis. United States.
Etats-Unis. United States.