Historique
Périodique
Treatment of out-patients with complicated benzodiazepine dependence: comparison of two approaches
(Traitement ambulatoire de la dépendance aux benzodiazépines : comparaison de deux approches.)
Auteur(s) :
VORMA, H. ;
NAUKKARINEN H. ;
SARNA S. ;
KUOPPASALMI, K.
Année
2002
Page(s) :
851-859
Langue(s) :
Anglais
Refs biblio. :
39
Domaine :
Autres substances / Other substances
Thésaurus mots-clés
BENZODIAZEPINES
;
DESINTOXICATION
;
CURE DE DESINTOXICATION
;
TRAITEMENT AMBULATOIRE
;
EFFICACITE
;
COMPARAISON
Note générale :
Addiction, 2002, 97, (7), 851-859
Note de contenu :
tabl.
Résumé :
FRANÇAIS :
76 patients consommant de fortes doses de benzodiazépines (BZD) seules ou avec de l'alcool, ont reçu soit un traitement standard soit un traitement expérimental (diminution graduelle des doses de BZD et thérapie cognitivo-comportementale). L'évaluation des traitements qui a porté sur 12 mois, ne montre pas de différences significatives entre les deux groupes : 13% des patients du groupe expérimental ont arrêté leur consommation de BZD, contre 27% du groupe standard et respectivement 67% l'ont diminué contre 57%.
ENGLISH :
Aims. To evaluate whether gradual benzodiazepine taper combined with cognitive-behavioural treatment is more effective than standard treatment for patients with dependence in out-patient clinics. Design. A randomized. controlled clinical trial, using standard questionnaires and serum and urine tests. Settings Four public-sector out-patient clinics for alcohol and drug abusers in Helsinki. Participants. Seventy-six patients with benzodiazepine dependence (DSM- III-R). Patients taking high doses of the drug or with alcohol use disorders were included to obtain a subject group representative of usual clinical practice. Intervention. Subjects received gradual benzodiazepine taper combined with cognitive-behavioural therapy (experimental group) or standard withdrawal treatment not scheduled by the researchers (control group). Measurements The outcome was measured in terms of attaining a state of abstinence or by a decrease in the dosage during the study period of up to 12 months' duration. Findings. No statistically significant differences in the outcomes were observed between the groups. A total of 13% of the experimental group and 27% of the control group were able to discontinue drug use. In addition 67% of the experimental group and 57% of the control group were able to decrease the dose. Conclusions. The search continues for improved methods of helping patients with complicated benzodiazepine dependence. (Author' s abstract)
76 patients consommant de fortes doses de benzodiazépines (BZD) seules ou avec de l'alcool, ont reçu soit un traitement standard soit un traitement expérimental (diminution graduelle des doses de BZD et thérapie cognitivo-comportementale). L'évaluation des traitements qui a porté sur 12 mois, ne montre pas de différences significatives entre les deux groupes : 13% des patients du groupe expérimental ont arrêté leur consommation de BZD, contre 27% du groupe standard et respectivement 67% l'ont diminué contre 57%.
ENGLISH :
Aims. To evaluate whether gradual benzodiazepine taper combined with cognitive-behavioural treatment is more effective than standard treatment for patients with dependence in out-patient clinics. Design. A randomized. controlled clinical trial, using standard questionnaires and serum and urine tests. Settings Four public-sector out-patient clinics for alcohol and drug abusers in Helsinki. Participants. Seventy-six patients with benzodiazepine dependence (DSM- III-R). Patients taking high doses of the drug or with alcohol use disorders were included to obtain a subject group representative of usual clinical practice. Intervention. Subjects received gradual benzodiazepine taper combined with cognitive-behavioural therapy (experimental group) or standard withdrawal treatment not scheduled by the researchers (control group). Measurements The outcome was measured in terms of attaining a state of abstinence or by a decrease in the dosage during the study period of up to 12 months' duration. Findings. No statistically significant differences in the outcomes were observed between the groups. A total of 13% of the experimental group and 27% of the control group were able to discontinue drug use. In addition 67% of the experimental group and 57% of the control group were able to decrease the dose. Conclusions. The search continues for improved methods of helping patients with complicated benzodiazepine dependence. (Author' s abstract)
Affiliation :
Ntal Public Hlth Inst., Dept Mental Hlth Alcohol Res., Mannerheimintle 166, FIN-00300 Helsinki
Finlande. Finland.
Finlande. Finland.