Historique
Périodique
Chasing the dragon, related to the impaired lung function among heroin users
(Inhalation d'héroïne ("chasser le dragon") et atteinte de la fonction respiratoire chez les héroïnomanes)
Auteur(s) :
BUSTER, M. C. A. ;
ROOK L. ;
VAN BRUSSEL, G. H. A. ;
VAN REE, J. M. ;
VAN DEN BRINK, W.
Année
2002
Page(s) :
221-228
Langue(s) :
Anglais
Refs biblio. :
34
Domaine :
Plusieurs produits / Several products
Note générale :
Drug and Alcohol Dependence, 2002, 68, (2), 221-228
Note de contenu :
graph. ; tabl.
Résumé :
ENGLISH :
Aim: To describe the pulmonary function and prevalence of dyspnoea among methadone patients and to study the relation with exposure to heroin by inhaling. Study population: A sample of 100 patients from methadone maintenance treatment (84% male, average age 42 years). Measurements: Questionnaires were used to measure life-time exposure to heroin, cocaine, cannabis, tobacco, and symptoms of dyspnoea. Spirometry was performed and residual difference of measured FEV1 from the age, sex, height and ethnicity predicted value (Delta-FEV1) was used as a main outcome parameter. Findings: The median Delta-FEV1 was -0.261 (inter quartile range -0.70; +0.I2). Twenty per cent experienced dyspnoea while `walking at a normal pace with someone of their own age. History of cigarette smoking was reported by 98%; heroin smoking by 88%. Multiple linear regression analysis showed a statistically significant association between heroin-smoking and Delta-FEV1, logistic regression analysis showed an association between heroin-smoking and prevalence of dyspnoea. Conclusions: Chronic heroin smoking seems to be related to an impaired lung function and higher prevalence of dyspnoea. However, part of the observed lung function impairment will be caused by tobacco smoking. Further research is needed to quantify the effect of heroin smoking and disentangle the effect of smoking heroin and tobacco. (Review's abstract.)
Affiliation :
Municipal Health Serv., Dept Epidemiol., PO Box 2200, 1000 CE Amsterdam
Pays-Bas. Netherlands.
Pays-Bas. Netherlands.