Historique
Périodique
Tramadol post-marketing surveillance in health care professionals
(Surveillance de l'usage du Tramadol chez les professionnels de santé après sa mise sur le marché)
Auteur(s) :
KNISELY J. S. ;
CAMPBELL, E. D. ;
DAWSON, K. S. ;
SCHNOLL, S. H.
Année
2002
Page(s) :
15-22
Langue(s) :
Anglais
Refs biblio. :
20
Domaine :
Autres substances / Other substances
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
ANALGESIQUES
;
POTENTIEL ADDICTIF
;
PERSONNEL MEDICAL
;
MESUSAGE
Thésaurus géographique
ETATS-UNIS
Note générale :
Drug and Alcohol Dependence, 2002, 68, (1), 15-22
Note de contenu :
tabl.
Résumé :
ENGLISH :
Tramadol has been marketed in the US since 1995. The US Food and Drug Administration agreed to release tramadol as a non-scheduled drug if proactive post-marketing surveillance studies would be conducted. This study was one of two phase IV protocols that were part of the overall surveillance program. It focused on impaired health professionals who are a high risk/high access population for drug abuse. All active participants in four state monitoring programs between November 1, 1995 and August 15, 199 (n = 1601) were recruited for the study. With the exceptions of implementing a standardized intake interview and urine testing for tramadol metabolites, all states operated their programs in the usual fashion. The programs were alerted to persistent non-prescribed tramadol use so that appropriate interventions could be employed. Despite availability of tramadol and the conditions that might lead to its abuse, the incidence rate for tramadol use in the study population was only 69 per thousand persons per year and the incidence rate for tramadol abuse or dependence was 6.9 per thousand persons per year. (Review's abstract.)
Affiliation :
Dept. Psychiatr. Internal Med., VA Commonwealth Univ., Po Box 980109, Richmond, VA 23298-0109
Etats-Unis. United States.
Etats-Unis. United States.