Historique
Périodique
Preventing problems in ecstasy users: reduce use to reduce harms
(Prévenir les problèmes chez les usagers d'ecstasy : réduire l'usage pour réduire les dommages)
Auteur(s) :
BAGGOTT, M. J.
Année
2002
Page(s) :
145-162
Langue(s) :
Anglais
Refs biblio. :
167
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
MDMA-ECSTASY
;
TOXICITE
;
EFFET SECONDAIRE
;
NEUROBIOLOGIE
;
REDUCTION DES RISQUES ET DES DOMMAGES
;
PREVENTION
;
FACTEUR DE RISQUE
;
PHYSIOLOGIE
Thésaurus géographique
ETATS-UNIS
Note générale :
Journal of Psychoactive Drugs, 2002, 34, (2), 145-162
Note de contenu :
tabl.
Résumé :
ENGLISH :
Increasing use of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") has been accompanied by concern about acute and possible long-term toxicity. This article discusses acute serious toxicity, chronic toxicity, and common problems associated with Ecstasy use, as well as the implications of these areas for prevention programs targeted at current Ecstasy users. The low incidence of serious adverse events in users creates difficulties for attempts to develop harm reduction recommendations. Many hypothesized risk factors for serious adverse events cannot be confirmed or denied and may not be associated with dramatic elevations in risk. Research on chronic toxicity in users provides strong evidence of neurophysiological changes and suggestive evidence of possible neurocognitive changes. Because these worrisome changes are clinically subtle, users may not be influenced by concerns of neurotoxicity. In contrast, common Ecstasy-related complaints are relatively well documented and have identified risk factors, including factors relating to extent of Ecstasy use (such as "binges"). Common complaints include modest acute and subacute adverse effects, some lasting several days, and problems in life. The apparent willingness of users to modify drug use and other behaviors to decrease these common problems could be used by harm reduction or other prevention programs to encourage users to decrease the extent of Ecstasy use. (Author's abstract.)
Affiliation :
75 Brosnan St, San Francisco, CA 94103
mattbaggott.net
Etats-Unis. United States.
mattbaggott.net
Etats-Unis. United States.