Historique
Périodique
Amlodipine reduces blood pressure and headhache frequency in cocaine-dependent outpatients
(L'amlodipine réduit la pression sanguine et la fréquence des maux de tête chez les cocaïnomanes)
Auteur(s) :
MALCOM R. ;
LIAO, J. ;
MICHEL, M. ;
COCHRAN K. ;
PYE W. ;
YEAGER D. ;
HALUSHKA P. V.
Année
2002
Page(s) :
415-419
Langue(s) :
Anglais
Refs biblio. :
32
Domaine :
Drogues illicites / Illicit drugs
Note générale :
Journal of Psychoactive Drugs, 2002, 34, (4), 415-419
Note de contenu :
tabl.
Résumé :
ENGLISH :
Blood pressure and headache frequency were evaluated in normotensive male and female cocaine-dependent patients (N=43) participating in a placebo-controlled, double-blind trial of amlodipine for the treatment of cocaine dependence. Amlodipine produced a significant reduction in both systolic (p=0.04) and diastolic (p=0.01) blood pressures without producing dizziness or faintness. Placebo subjects had about three times the frequency of headaches compared to the amlodipine-treated subjects (p=0.004). The high frequency of headaches reported by cocaine-dependent individuals was significantly reduced by amlodipine and may reflect improved cerebrovascular tone. (Author's abstract.)
Affiliation :
Ctr Drug Alc. Prog., 67 Pdt St, Charleston, SC 29425
malcomrmusc.edu
Etats-Unis. United States.
malcomrmusc.edu
Etats-Unis. United States.