Historique
Périodique
Effects of HIV triple therapy on methadone levels
(Les effets de la tri-thérapie sur les taux sanguins en méthadone.)
Auteur(s) :
AKERELE, E. O. ;
LEVIN, F. ;
NUNES, E. ;
BRADY, R. ;
KLEBER, H.
Année
2002
Page(s) :
308-314
Langue(s) :
Anglais
Refs biblio. :
21
Domaine :
Drogues illicites / Illicit drugs
Note générale :
American Journal on Addictions, 2002, 11, (4), 308-314
Note de contenu :
graph. ; tabl.
Résumé :
ENGLISH :
There is a belief among methadone patients that triple therapy for HIV reduces methadone potency. This cross-sectional study compared the rate of methadone metabolism (peak-trough blood levels) in two groups of methadone-maintained patients, AIDS patients receiving triple therapy (N=17), and HIV patients without triple therapy (N=19). These preliminary findings suggest that triple therapy may increase the rate of methadone metabolism, though further studies are warranted. (Author' s abstract)
Affiliation :
Div. of Substance Use, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia Univ., 1051 Riverside Drive, New York, NY 10032. Email : akerele@pi.cpmc.columbia.edu
Etats-Unis. United States.
Etats-Unis. United States.