Historique
Périodique
Research advances in the understanding and treatment of addiction
(Les avancées de la recherche dans la compréhension de l'addiction et en matière de traitement.)
Auteur(s) :
O'BRIEN, C. P.
Année
2003
Page(s) :
S36-S47
Langue(s) :
Anglais
Refs biblio. :
30
Domaine :
Plusieurs produits
Thésaurus mots-clés
ADDICTION
;
RECHERCHE
;
MECANISME D'ACTION
;
TRAITEMENT
;
SYNDROME DE SEVRAGE
;
RECHUTE
Note générale :
American Journal on Addictions, 2003, 12, (Supp. 2), S36-S47
Note de contenu :
tabl.
Résumé :
ENGLISH :
The likelihood of developing an addictive disorder is a function of multiple simultaneous, pharmacologic, genetic, and environmental variables, such as the pharmacology of the drug, the route of administration, the personality of the individual, and the availability of the drug. There is increasing evidence that long-lasting changes in the brain result from the progression of casual user to addict. Moreover, the course of the progression of addiction is similar to that of other chronic diseases. In this payer, strategies for effective treatment of addiction, including long-term relapse management and new pharmacological therapies such as naltrexone and acamprosate, are discussed. (Author' s abstract)
Affiliation :
Univ. of Pennsylvania, VA Medical Center, 3900 Chestnut Street, Philadelphia, PA 19104-6178. Email : obrienmail.trc.upenn.edu
Etats-Unis. United States.
Etats-Unis. United States.