Historique
Périodique
The use of tramadol for acute heroin withdrawal : a comparison to clonidine
(L'utilisation du tramadol dans le sevrage précipité de l'héroïne : une comparaison avec la clonidine.)
Auteur(s) :
SOBEY P. W. ;
PARRAN JR., T. V. ;
GREY S. F. ;
ADELMAN, C. L. ;
YU, J.
Année
2003
Page(s) :
13-25
Langue(s) :
Anglais
Refs biblio. :
41
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
SEVRAGE
;
HEROINE
;
CLONIDINE
;
ANTIDEPRESSEURS
;
EFFICACITE
;
COMPARAISON
;
ETUDE RETROSPECTIVE
Note générale :
Journal of Addictive Diseases, 2003, 22, (4), 13-25
Note de contenu :
graph. ; tabl.
Résumé :
ENGLISH :
Using a retrospective chart review, 59 patients detoxified with tramadol were compared to 85 patients detoxified with clonidine on rates of leaving against medical advice (AMA) and control of withdrawal symptoms. Patients detoxified with tramadol had 23% (95% CI, 0.09-0.59 ; P < .01) the risk of leaving AMA and scored an average of 0.24 points lower (95% CI, 0.08-0.41 ; P < .01) on a 0-3 point withdrawal symptom scale compared to patients detoxified with clonidine. This preliminary study indicates that tramadol is more effective in managing withdrawal than clonidine, and may be especially useful in outpatient detoxification. (Review' s abstract)
Affiliation :
Dptmt. Family Med., Univ. Hospitals Cleveland and Cleveland
Etats-Unis. United States.
Etats-Unis. United States.