Historique
Périodique
Sensitization to the psychosis-inducing effects of cocaine compared with measures of cocaine craving and cue reactivity
(Comparaison de la sensibilisation aux effets psychotiques induits par la cocaïne à des mesures du manque et de la réactivité à des incitations d'usage.)
Auteur(s) :
REID, M. S. ;
CIPLET D. ;
O'LEARY, S. ;
BRANCHEY M. ;
BUYDENS-BRANCHEY L. ;
ANGRIST, B.
Année
2004
Page(s) :
305-315
Langue(s) :
Anglais
Refs biblio. :
19
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
COCAINE
;
TROUBLE BIPOLAIRE
;
BIOSENSIBILISATION
;
PSYCHOSE
;
RECHUTE
;
MANQUE
;
FACTEUR DE RISQUE
Note générale :
American Journal on Addictions, 2004, 13, (3), 305-315
Note de contenu :
fig. ; tabl.
Résumé :
ENGLISH :
A previous study has suggested that sensitization to the psychosis-inducing effects of cocaine may be a marker of vulnerability to relapse in cocaine addiction. In this report, cocaine-dependent subjects participating in a study on naturally occurring and cue-induced cocaine craving were interviewed about prior experience of cocaine-induced psychosis and the degree to which this sect had become more frequent or severe or had occurred at lower-cumulative doses. Sensitization to cocaine-induced psychosis was negatively correlated with base-line measures of drug dependence severity and indices of cocaine craving over the preceding 24 hours but not with measures of cocaine cue reactivity. (Author' s abstract)
Affiliation :
Psychiatry Serv. 116, VA New York Harbor Healthcare System, 423 East 23rd Street, New York, NY 10010. E-mail: malcolm.reidmed.va.gov
Etats-Unis. United States.
Etats-Unis. United States.