Historique
Article de Périodique
Methylphenidate effective in treating amphetamine abusers with no other psychiatric disorder (2005)
(Efficacité du méthylphénidate dans le traitement de la dépendance aux amphétamines chez les personnes ne présentant aucun autre trouble psychiatrique)
Auteur(s) :
LAQUEILLE, X. ;
DERVAUX, A. ;
EL OMARI F. ;
KANIT, M. ;
BAYLE, F. J.
Année
2005
Page(s) :
456-457
Langue(s) :
Anglais
Refs biblio. :
5
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
METHYLPHENIDATE
;
TDAH
;
AMPHETAMINE
;
DEPENDANCE
;
TRAITEMENT
;
ETUDE DE CAS
;
EFFICACITE
Résumé :
Medical treatment of amphetamine abuse is difficult due to the lack of an effective way of treating withdrawal symptoms, lack of appetency therapy, and the lack of maintenance therapy. Preliminary studies have suggested the idea of a maintenance therapy for amphetamine and cocaine dependencies. Long-acting amphetamines could be used in a manner analogous to methadone in the abuse of opiates and nicotinic substitutes for tobacco dependence. In the 1960s, anorectic stimulant drugs were prescribed widely in France. Because of misuse and abuse, the medical use of amphetamines was banned in 1999 by the French government. We report on four cases of amphetamine abuse, according to DSM-IV criteria, that were treated with methylphenidate 20/40 mg/day for at least 3 years. The patients gave their consent after receiving information on the goals of methylphenidate therapy, its type of action, and its side effects. No contra-indications were given for methylphenidate therapy after the clinical somatic and psychiatric examination of the patients. None of them showed any signs of juvenile or adult attention-deficit/hyperactivity disorder (ADHD) according to DSM-IV criteria. This diagnostic was evaluated using corresponding items from the Diagnostic Interview Schedule (DIS) and the Wender Utah Rating Scale (WURS). [Extract]
Affiliation :
Université Paris V, CH Sainte-Anne, SHU, 1 rue Cabanis 75674 Paris cedex
France
France