Titre : | Hepatitis B virus in drug users in France: prevalence and vaccination history, ANRS-Coquelicot Survey 2011-2013 (2017) |
Auteurs : | C. BROUARD ; J. PILLONEL ; P. SOGNI ; A. CHOLLET ; J. V. LAZARUS ; X. PASCAL ; F. BARIN ; M. JAUFFRET-ROUSTIDE |
Type de document : | Article : Périodique |
Dans : | Epidemiology and Infection (Vol.145, n°6, April 2017) |
Article en page(s) : | 1259-1269 |
Langues: | Anglais |
Discipline : | MAL (Maladies infectieuses / Infectious diseases) |
Mots-clés : |
Thésaurus géographique FRANCEThésaurus mots-clés ENQUETE ; HEPATITE ; PREVALENCE ; VACCINATION ; ETUDE TRANSVERSALE ; DEPISTAGE ; USAGER ; INJECTION ; PROFIL SOCIO-DEMOGRAPHIQUE ; PRODUIT ILLICITE ; CONDUITE A RISQUE ; INFECTION |
Résumé : | People who use drugs (PWUD) are a key population for hepatitis B virus (HBV) vaccination and screening. We aimed to estimate the seroprevalence of HBs antigen (HBsAg) and self-reported HBV vaccination history in French PWUD attending harm reduction centres using data from the ANRS-Coquelicot multicentre survey conducted in 2011-2013 in 1718 PWUD. Self-fingerprick blood samples were collected on dried blood spots to detect the presence of HBsAg. HBsAg seroprevalence was estimated at 1.4% [95% confidence interval (CI) 0.8-2.5]. It varied between PWUD born in high (7.6%, 95% CI 2.7-19.1), moderate (2.2%, 95% CI 0.8-5.7) and low (0.7%, 95% CI 0.3-1.5) endemic zones. Factors independently associated with HBsAg carriage were being born in a moderate or high endemic zone or reporting precarious housing. Self-reported HBV vaccination history varied from 47.4% in high endemic zones, to 59.3% and 62.6% for moderate and low endemic zones, respectively. Our results suggest that drug use plays a small and substantial role, respectively, in HBsAg carriage in PWUD born in high/moderate and low endemic zones. |
Domaine : | Drogues illicites / Illicit drugs |
Affiliation : | Santé publique France, Direction des Maladies Infectieuses, Saint-Maurice, France |
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