Titre : | Relationship between cannabis and psychosis: Reasons for use and associated clinical variables (2015) |
Auteurs : | A. MANÉ ; M. FERNANDEZ-EXPOSITO ; D. BERGÉ ; L. GOMEZ-PEREZ ; A. SABATÉ ; A. TOLL ; L. DIAZ ; C. DIEZ-AJA ; V. PEREZ |
Type de document : | Article : Périodique |
Dans : | Psychiatry Research (Vol.229, n°1-2, 30 September 2015) |
Article en page(s) : | 70-74 |
Langues: | Anglais |
Discipline : | PSY (Psychopathologie / Psychopathology) |
Mots-clés : |
Thésaurus mots-clés TROUBLE BIPOLAIRE ; ETUDE CLINIQUE ; CANNABIS ; PSYCHOSE ; SCHIZOPHRENIE ; AUTOMEDICATION ; PSYCHOPATHOLOGIE ; AGE ; MOTIVATIONThésaurus géographique ESPAGNE |
Résumé : |
The mechanism underneath the relationship between cannabis and psychosis remains controversial, for which several hypotheses have been proposed, including cannabis as self-medication and cannabis as a risk for the development of psychosis. The aim of this work was to study the relationship between cannabis and psychosis in first-episode psychosis cannabis users and non-users, and non-psychotic cannabis users. The age at the first psychotic episode, duration of untreated psychosis, psychopathology and reasons for cannabis use were assessed. First-episode psychosis cannabis users showed an earlier age at psychosis onset than non-user patients. No significant differences in symptomatology were found. The distinguishing reasons to use cannabis for patients with first-episode psychosis with respect to non-psychotic users were to arrange their thoughts and deal with hallucinations and suspiciousness. These findings are in agreement with both hypotheses: self-medication and secondary psychosis hypothesis. However, longitudinal prospective cohort studies assessing reasons for cannabis use are needed to investigate both hypotheses and their complementarity.
Highlights: First-episode psychosis cannabis users showed an earlier age at psychosis onset than non-users. First-episode psychosis patients had distinguishing reasons to use cannabis. |
Domaine : | Drogues illicites / Illicit drugs |
Affiliation : | IMIM (Hospital del Mar Medical Research Institute) - Neurosciences, Psychiatry, Barcelona, Spain |
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