Titre : | Cannabis use and vulnerability for psychosis in early adolescence - A TRAILS study (2013) |
Auteurs : | M. F. H. GRIFFITH-LENDERING ; J. T. W. WIGMAN ; A. PRINCE VAN LEEUWEN ; S. C. J. HUIJBREGTS ; A. C. HUIZINK ; J. ORMEL ; F. C. VERHULST ; J. VAN OS ; H. SWAAB ; W. A. M. VOLLEBERGH |
Type de document : | Article : Périodique |
Dans : | Addiction (Vol.108, n°4, April 2013) |
Article en page(s) : | 733-740 |
Note générale : | Commentary: Cross-lagging cannabis and psychosis vulnerability. Lewis G., Heron J., Zammit S., p. 741-742. |
Langues: | Anglais |
Discipline : | PSY (Psychopathologie / Psychopathology) |
Mots-clés : |
Thésaurus mots-clés TROUBLE BIPOLAIRE ; CANNABIS ; PSYCHOSE ; ADOLESCENT ; FACTEUR DE VULNERABILITE ; ETUDE PROSPECTIVEThésaurus géographique PAYS-BAS |
Résumé : |
Aims - To examine the direction of the longitudinal association between vulnerability for psychosis and cannabis use throughout adolescence.
Design - Cross-lagged path analysis was used to identify the temporal order of vulnerability for psychosis and cannabis use, while controlling for gender, family psychopathology, alcohol use and tobacco use. Setting - A large prospective population study of Dutch adolescents [the TRacking Adolescents' Individual Lives Survey (TRAILS) study]. Participants - A total of 2120 adolescents with assessments at (mean) age 13.6, age 16.3 and age 19.1. Measurements - Vulnerability for psychosis at the three assessment points was represented by latent factors derived from scores on three scales of the Youth Self-Report and the Adult Self-Report, i.e. thought problems, social problems and attention problems. Participants self-reported on cannabis use during the past year at all three waves. Findings - Significant associations (r = 0.12–0.23) were observed between psychosis vulnerability and cannabis use at all assessments. Also, cannabis use at age 16 predicted psychosis vulnerability at age 19 (Z = 2.6, P Conclusions - Cannabis use predicts psychosis vulnerability in adolescents and vice versa, which suggests that there is a bidirectional causal association between the two. KEY FINDINGS: Cannabis use predicts psychosis vulnerability among Dutch adolescents, and vice versa. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 52 |
Affiliation : | Department of Clinical Child and Adolescent Studies, Faculty of Social Sciences, Leiden University, Leiden, the Netherlands |
Cote : | Abonnement |
Lien : | http://dx.doi.org/10.1111/add.12050 |
Accueil