Titre : | Mephedrone: use, subjective effects and health risks (2011) |
Titre traduit : | (Méphédrone : usage, effets subjectifs et risques pour la santé) |
Auteurs : | A. WINSTOCK ; L. MITCHESON ; J. RAMSEY ; S. DAVIES ; M. PUCHNAREWICZ ; J. MARSDEN |
Type de document : | Article : Périodique |
Dans : | Addiction (Vol.106, n°11, November 2011) |
Article en page(s) : | 1991-1996 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus géographique ROYAUME-UNIThésaurus mots-clés MEPHEDRONE ; ETUDE TRANSVERSALE ; TELEPHONE ; ENQUETE ; TOXICOLOGIE ; EFFET SECONDAIRE ; CONSOMMATION ; PREVALENCE ; DEPENDANCE |
Résumé : |
AIMS To assess the patterns of use, subjective effect profile and dependence liability of mephedrone, supported by corroborative urine toxicology.
DESIGN Cross-sectional structured telephone interview. Setting UK-based drug users associated with the dance music scene. PARTICIPANTS A total of 100 mephedrone users, recruited through their involvement with the dance music scene. MEASUREMENTS Assessment of pattern of use, acute and after effects, DSM dependence criteria and gas chromatography-mass spectrometry urinalysis. FINDINGS Mephedrone consumption results in typical stimulant-related subjective effects: euphoria, increased concentration, talkativeness, urge to move, empathy, jaw clenching, reduced appetite and insomnia. Thirty per cent of the sample potentially met criteria for DSM-IV dependence and there was evidence of a strong compulsion to use the drug (47% had used the drug for 2 or more consecutive days). Self-reported recent consumption of mephedrone was confirmed by toxicological analysis in all of the 14 participants who submitted a urine sample. CONCLUSION Mephedrone has a high abuse and health risk liability, with increased tolerance, impaired control and a compulsion to use, the predominant reported dependence symptoms. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 13 |
Affiliation : | Addictions Department, Institute of Psychiatry, King's College London, United Kingom |
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