Titre : | A case report: Pavlovian conditioning as a risk factor of heroin 'overdose' death (2005) |
Titre traduit : | (Etude de cas : le réflexe conditionné de Pavlov comme facteur de risque d'un décès à l'héroïne par "overdose") |
Auteurs : | J. GEREVICH ; E. BACSKAI ; L. FARKAS ; DANICS Z. |
Type de document : | Article : Périodique |
Dans : | Harm Reduction Journal (Vol.2 n°11, 2005) |
Article en page(s) : | 4 p. |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus mots-clés ETUDE DE CAS ; HEROINE ; SURDOSE ; CONDITIONNEMENT ; MORT ; AUTOPSIE ; MORPHINE ; MESURES QUANTITATIVESThésaurus géographique HONGRIE |
Résumé : |
Background: The authors present a case illustrating a mechanism leading directly to death which is not rare but has received little attention.
Case presentation: The case was evaluated by autopsy, investigation of morphine concentration in the blood, and clinical data. The heroin dose causing the 'overdose' death of a young man who had previously been treated a number of times for heroin addiction did not differ from his dose of the previous day taken in the accustomed circumstances. The accustomed dose taken in a strange environment caused fatal complications because the conditioned tolerance failed to operate. The concentration of morphine in the blood did not exceed the level measured during earlier treatment. Conclusion: These results are in line with the data in the literature indicating that morphine concentrations measured in cases of drug-related death do not differ substantially from those measured in cases where the outcome is not fatal. A knowledge of the conditioning mechanism can contribute to prevention of fatal cases of a similar type. The harm reduction approach places great stress on preventive intervention based on data related to drug-related death. |
Domaine : | Drogues illicites / Illicit drugs |
Sous-type de document : | Etude de cas / Case report |
Refs biblio. : | 12 |
Affiliation : | Addiction Research Institute, Budapest, Hungary |
Numéro Toxibase : | 1301500 |
Lien : | https://doi.org/10.1186/1477-7517-2-11 |
Accueil