Titre : | Acute neonatal effects of cocaine exposure during pregnancy (2005) |
Titre traduit : | (Effets aigus néonataux de l'exposition à la cocaïne durant la grossesse) |
Auteurs : | C. R. BAUER ; J. C. LANGER ; SHANKARAN S. ; H. S. BADA ; B. LESTER ; L. L. WRIGHT ; H. KRAUSE-STEINRAUF ; SMERIGLIO V. L. ; L. P. FINNEGAN ; MAZA P. L. ; VERTER J. |
Type de document : | Article : Périodique |
Dans : | Archives of Pediatrics and Adolescent Medicine (Vol.159, n°9, September 2005) |
Article en page(s) : | 824-834 |
Langues: | Anglais |
Discipline : | PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods) |
Mots-clés : |
Thésaurus mots-clés COCAINE ; GROSSESSE ; NOUVEAU-NE ; ETUDE PROSPECTIVE ; SYMPTOME ; DEPISTAGEThésaurus géographique ETATS-UNIS |
Résumé : | OBJECTIVE: To identify associations between cocaine exposure during pregnancy and medical conditions in newborn infants from birth through hospital discharge. DESIGN: Multisite, prospective, randomized study. SETTING: Brown University, University of Miami, University of Tennessee (Memphis), and Wayne State University.Subjects A total of 717 cocaine-exposed infants and 7442 nonexposed infants. MAIN OUTCOME MEASURES: Results of physical examination and conditions observed during hospitalization. RESULTS: Cocaine-exposed infants were about 1.2 weeks younger, weighed 536 g less, measured 2.6 cm shorter, and had head circumference 1.5 cm smaller than nonexposed infants (all P<.001 results did not confirm previously reported abnormalities. central and autonomic nervous system symptoms were more frequent in the exposed group: jittery odds ratio confidence interval high-pitched cry irritability excessive suck hyperalertness instability no differences detected organ systems by ultrasound examination. infants had infections including hepatitis syphilis human immunodeficiency virus exposure less often breastfed child protective services referrals living with their biological mother conclusions: cohort persisted an adjusted analysis. they usually transient may be a true cocaine effect. abnormal anatomic outcomes confirmed. increased particularly sexually transmitted diseases pose serious public health challenge. involvement of out-of-home placement.> |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 47 |
Affiliation : | Department of Pediatrics, University of Miami School of Medicine, Miami, FL 33101, USA |
Numéro Toxibase : | 1301662 |
Centre Emetteur : | 13 OFDT |
Cote : | A02823 |
Lien : | https://doi.org/10.1001/archpedi.159.9.824 |
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