Titre : | Psychotropic analgesic nitrous oxide for acute cocaine withdrawal in man |
Titre traduit : | (L'oxyde nitrique analgésique psychotrope dans le sevrage aigu de la cocaïne chez l'homme) |
Auteurs : | GILLMAN M. A. ; LICHTIGFELD F. J. ; HARKER N. |
Type de document : | Périodique |
Année de publication : | 2006 |
Format : | 847-857 |
Note générale : |
International Journal of Neuroscience, 2006, 116, (7), 847-857 |
Langues: | Français |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés PROTOXYDE D'AZOTE ; ETUDE DE CAS ; ANALGESIQUES ; COCAINE ; SEVRAGE ; EFFICACITEThésaurus géographique AFRIQUE DU SUD |
Résumé : |
ENGLISH : This article reports the first single-blind study using psychotropic analgesic nitrous oxide (PAN) for treating acute withdrawal states following cocaine abuse. Thirty-one of the 33 cases responded by a reduction of symptom scores of 50% or more, which clinical experience has shown to be synonymous with observed recovery. Five subjects were placebo responders without further improvement following PAN. Eleven subjects were not improved by placebo but responded positively to PAN. Fifteen responded to both the O2 with a further improvement following PAN. Aggregate scores of symptoms such as craving, anxiety, and dysphoria were greatly decreased by O2. These improvements were even greater following PAN as compared to post O2 scores. Two patients failed to respond to any treatment condition. Thus 93.9% of the subjects were improved by the use of PAN and/or O2 alone. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 34 |
Affiliation : |
South African Brain Research Institute, Johannesburg. Email : mag@iafrica.com Afrique du Sud. South Africa. |
Numéro Toxibase : | 1301862 |
Centre Emetteur : | 13 OFDT |
Cote : | A02910 |
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