Titre : | Triggering myocardial infarction by marijuana (2001) |
Titre traduit : | (Le déclenchement d'un infarctus du myocarde par de la marijuana) |
Auteurs : | M. A. MITTLEMAN ; R. A. LEWIS ; M. MACLURE ; J. B. SHERWOOD ; J. E. MULLER |
Type de document : | Article : Périodique |
Dans : | Circulation (Vol.103, n°23, June 12, 2001) |
Article en page(s) : | 2805-2809 |
Langues: | Anglais |
Discipline : | PAT (Pathologie organique / Organic pathology) |
Mots-clés : |
Thésaurus mots-clés CANNABIS ; MECANISME D'ACTION ; COEUR ; INFARCTUS ; ETUDE TRANSVERSALEThésaurus géographique ETATS-UNIS |
Résumé : | BACKGROUND: Marijuana use in the age group prone to coronary artery disease is higher than it was in the past. Smoking marijuana is known to have hemodynamic consequences, including a dose-dependent increase in heart rate, supine hypertension, and postural hypotension; however, whether it can trigger the onset of myocardial infarction is unknown. METHODS AND RESULTS: In the Determinants of Myocardial Infarction Onset Study, we interviewed 3882 patients (1258 women) with acute myocardial infarction an average of 4 days after infarction onset. We used the case-crossover study design to compare the reported use of marijuana in the hour preceding symptoms of myocardial infarction onset to its expected frequency using self-matched control data. Of the 3882 patients, 124 (3.2%) reported smoking marijuana in the prior year, 37 within 24 hours and 9 within 1 hour of myocardial infarction symptoms. Compared with nonusers, marijuana users were more likely to be men (94% versus 67%, P |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 35 |
Affiliation : | Institute for the Prevention of Cardiovascular Disease, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA |
Centre Emetteur : | 13 OFDT |
Cote : | A03083 |
Lien : | http://dx.doi.org/10.1161/01.CIR.103.23.2805 |
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