Titre : | Maintenance treatment with depot opioid antagonists in subcutaneous implants: an alternative in the treatment of opioid dependence |
Titre traduit : | (Un traitement de maintenance par des implants sous-cutanés d'antagonistes opioïdes : une alternative dans le traitement de la dépendance aux opioïdes.) |
Auteurs : | J. E. CARRENO ; C. E. ALVAREZ ; G. I. SAN NARCISO ; M. T. BASCARAN ; DIAZ M. ; J. BOBES |
Type de document : | Périodique |
Année de publication : | 2003 |
Format : | 429-438 / fig. ; graph. ; ill. ; tabl. |
Note générale : |
Addiction Biology, 2003, 8, (4), 429-438 |
Langues: | Anglais |
Discipline : | TRA (Traitement et prise en charge / Treatment and care) |
Mots-clés : |
Thésaurus mots-clés TRAITEMENT DE MAINTENANCE ; NALTREXONE ; VOIE SOUSCUTANEE ; EFFICACITE |
Résumé : |
ENGLISH : A report is presented of treatment of 156 patients (male 98%) with opioid dependence (ICD-10 criteria) using a maintenance programme with depot opioid antagonists (naltrexone) as subcutaneous implants, started after an outpatient rapid antagonization regimen. The retention index in the treatment was from 80% in the sixth month, and 65 % after one year. The patients were followed-up for 1 year after discharge. For 6 months after discharge 55.4% were still returning for follow-up visits and 20.8% after 1 year, all of them remaining abstinent to opioids. It is concluded that the programme is safe for the patients and shows a better retention index than programmes using oral antagonists, with an improved compliance (negative urine analysis) compared to the latter. (Author' s abstract) |
Note de contenu : | fig. ; graph. ; ill. ; tabl. |
Domaine : | Drogues illicites / Illicit drugs |
Refs biblio. : | 54 |
Affiliation : |
Clinica Médico Psicologica Asturias, C/Asturias, 8-5a planta, 33206 Gijon, Asturias. Email : cmedicotelecable.es Espagne. Spain. |
Numéro Toxibase : | 207197 |
Centre Emetteur : | 02 Coordonnateur |
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